Vol. 1 No. 2 (2023)

Volume 1, Issue 2 spans computational biology, oncology, ophthalmology and public health. It presents an Excel-based template for identifying mouse myeloid cell types in the CNS via single-cell RNA sequencing, and a network pharmacology study comparing trehalose pharmacodynamics across human, mouse and rat models. The issue then addresses cancer immunology through a cytomorphological analysis of melanoma focusing on CTLA-4, PD-1 and PD-L1 expression, and a review of immune checkpoint inhibitors in triple-negative breast cancer. Clinically, it explores multimodal fundus imaging for central serous chorioretinopathy and examines the multifaceted drivers of vaccine hesitancy. Together, the articles reflect the journal's mission of bridging molecular discovery with medical and societal challenges.