Nature Cell and Science

Current Issue

Vol. 4 No. 4 (2026)
Published October 12, 2026
Issue Description

Volume 4, Issue 4 features studies spanning cannabinoid pharmacology and nanotherapeutic engineering. A review examines the medical applications and misuse potential of cannabis, tracing the pharmacological mechanisms of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) through the endocannabinoid system, their therapeutic benefits for chronic pain, multiple sclerosis spasticity, chemotherapy-induced nausea, and epilepsy, and the emerging challenges of tolerance, withdrawal, and cannabis use disorder, particularly among adolescents. Another review investigates the engineering of nanotherapeutics to target mechanotransduction, cellular senescence, and regenerative signaling in wound healing, highlighting how liposomes, polymeric nanoparticles, and multifunctional nanostructures enable precise drug delivery while modulating growth factor signaling, immune responses, and tissue repair. Together, the articles reflect the journal's commitment to publishing diverse research from molecular pharmacology and neurotransmitter signaling to advanced nanomedical platforms with translational implications.

Articles

Fernand Catherine Ferdinica, Rengasamy Rishikesh, Bhagavathi Sundaram Sivamaruthi, Fairen Angelin Jayakumar, Durairaj Ragu Varman
e00020
Medical Applications and Misuse Potential of Cannabis: Pharmacological Mechanisms, Therapeutic Benefits, and Clinical Challenges
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DOI: https://doi.org/10.61474/ncs.2026.00020
Rajiv Kumar, Gerardo Caruso, Thuan Duc Lao, Thuy Ai Huyen Le, Svetlana von Gratowski
e00031
Engineering nanotherapeutics to target mechanotransduction, senescence, and regenerative signaling
PDF
DOI: https://doi.org/10.61474/ncs.2026.00031
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